Table 2.
Antimicrobial susceptibility patterns of β-lactamase-producing Enterobacteriaceae
| Resistance to antimicrobial agents (%) |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β-lactamases | Isolates (No/total; %) | FEP |
Amp |
AMC |
PIZ |
SXT |
Am |
Gen |
CIP |
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| S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | ||
| ESBL | E. coli (75/219; 34.2) | 52.0 | 14.7 | 33.3 | 100 | 82.7 | 14.7 | 2.7 | 90.7 | 6.7 | 2.7 | 24.0 | 76.0 | 98.7 | 1.3 | 50.7 | 1.3 | 48.0 | 21.3 | 5.3 | 73.3 | ||||
| K. pneumoniae (37/57; 64.9) | 18.9 | 18.9 | 62.2 | 100 | 24.3 | 21.6 | 54.1 | 29.7 | 13.5 | 56.8 | 21.6 | 78.4 | 56.8 | 16.2 | 27.0 | 24.3 | 75.7 | 35.1 | 10.8 | 54.1 | |||||
| S. flexneri (2/2; 100) | 100 | 100 | 100 | 100 | 100 | 100 | 50.0 | 50.0 | 100 | ||||||||||||||||
| S. sonnei (2/2; 100) | 100 | 100 | 100 | 100 | 100 | 100 | 50.0 | 50.0 | 50.0 | 50.0 | |||||||||||||||
| AmpC | E. coli (14/219; 6.4) | 78.6 | 21.4 | 7.1 | 92.9 | 14.3 | 85.7 | 57.1 | 21.4 | 21.4 | 42.9 | 57.1 | 92.9 | 7.1 | 78.6 | 21.4 | 14.3 | 7.1 | 78.6 | ||||||
| E. cloacae (9/14; 64.3) | 88.9 | 11.1 | 11.1 | 88.9 | 22.2 | 77.8 | 100 | 66.7 | 33.3 | 100 | 88.9 | 11.1 | 55.6 | 44.4 | |||||||||||
| P. mirabilis (2/5; 40.0) | 100 | 50.0 | 50.0 | 100 | 100 | 50.0 | 50.0 | 100 | 50.0 | 50.0 | 100 | ||||||||||||||
| S. marcescens (1/1; 100) | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |||||||||||||||||
| M. morganii (2/2; 100) | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |||||||||||||||||
| ESBL+ AmpC | E. coli (9/219; 4.1) | 33.3 | 22.2 | 44.4 | 100 | 66.7 | 33.3 | 22.2 | 66.7 | 11.1 | 11.1 | 88.9 | 100 | 66.7 | 33.3 | 11.1 | 88.9 | ||||||||
| E. cloacae (5/14; 35.7) | 40.0 | 60.0 | 100 | 20.0 | 80.0 | 100 | 100 | 100 | 100 | 40.0 | 40.0 | 20.0 | |||||||||||||
| C. freundii (1/1; 100) | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |||||||||||||||||
| MBL | K. pneumoniae (9/57; 15.8) | 100 | 100 | 11.1 | 88.9 | 100 | 100 | 11.1 | 88.9 | 100 | 11.1 | 88.9 | |||||||||||||
| KPC | K. pneumoniae (4/57; 7.0) | 25.0 | 75.0 | 100 | 100 | 100 | 50.0 | 50.0 | 75.0 | 25.0 | 100 | 50.0 | 50.0 | ||||||||||||
| OXA-48 | K. pneumoniae (2/57; 3.5) | 100 | 100 | 100 | 100 | 100 | 50.0 | 50.0 | 100 | 50.0 | 50.0 | ||||||||||||||
| ESBL+ Decreased permeability | E. coli (2/219; 0.9) | 50.0 | 50.0 | 100 | 100 | 50.0 | 50.0 | 100 | 100 | 50.0 | 50.0 | 100 | |||||||||||||
| K. pneumoniae (5/57; 8.8) | 20.0 | 40.0 | 40.0 | 100 | 100 | 100 | 100 | 60.0 | 40.0 | 40.0 | 60.0 | 60.0 | 40.0 | ||||||||||||
| AmpC+ Decreased permeability | E. coli (4/219; 1.8) | 50.0 | 25.0 | 25.0 | 100 | 25.0 | 75.0 | 25.0 | 25.0 | 50.0 | 25.0 | 75.0 | 100 | 50.0 | 50.0 | 25.0 | 75.0 | ||||||||
| E. cloacae (1/14; 7.1) | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |||||||||||||||||
| P. mirabilis (2/5; 40.0) | 100 | 50.0 | 50.0 | 100 | 100 | 50.0 | 50.0 | 100 | 50.0 | 50.0 | 100 | ||||||||||||||
FEP, cefepime; Amp, ampicillin; AMC, amoxicillin/clavulanate; PIZ, piperacillin/tazobactam; SXT, terimethoprim/sulfamethoxazole; Am, amikacin; Gen, gentamicin; CIP, Ciprofloxacin; S, sensitive; R, resistant; I, intermediate.