Table 3.
Serum levels of glycaemic and insulinemic biomarkers at baseline compartment of study and 8 weeks after the intervention in women with BBT who received BV supplementation (BV group) versus placebo juice consumers (control).
| Variable |
Baseline (n = 40)
|
8-weeks follow-up (n = 40)
|
Absolute treatment effect
|
Relative treatment effect | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean | S.D. | P | n | Mean | S.D. | P | Mean | 95%CI | P c | ||
| Insulin (U/mL) | ||||||||||||
| Control | 39 | 0.38 | 0.33 | N/A | 39 | 0.50* | 0.17 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 35 | 0.49 | 0.43 | 0.09 | 35 | 0.51* | 0.22 | 0.72 | 0.10 | (-0.08-0.28) | 0.26 | 0.81 |
| C-peptide (ng/mL) | ||||||||||||
| Control | 40 | 2.27 | 1.06 | N/A | 40 | 2.97* | 1.13 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 40 | 2.56 | 1.12 | 0.23 | 40 | 3.42* | 1.44 | 0.16 | -0.15 | (-0.62-0.32) | 0.13 | 0.92 |
| FBS (mg/dL) d | ||||||||||||
| Control | 40 | 92.22 | 14.73 | N/A | 40 | 87.85 | 12.14 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 40 | 89.25 | 9.33 | 0.28 | 40 | 91.00 | 10.85 | 0.22 | -6.12 | (-12.7-0.50) | 0.97 | 1.06 |
| HOMA-IR e | ||||||||||||
| Control | 39 | 0.09 | 0.09 | N/A | 40 | 0.11 | 0.04 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 39 | 0.10 | 0.09 | 0.34 | 37 | 0.11 | 0.06 | 0.19 | 0.01 | (-0.03-0.06) | 0.44 | 0.84 |
| HOMB f | ||||||||||||
| Control | 39 | 13.30 | 49.87 | N/A | 39 | 9.69* | 6.54 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 36 | 10.26 | 15.86 | 0.05 | 36 | 9.80* | 9.49 | 0.05 | 375 | (21-730) | 0.86 | 1.44 |
| QUIKI g | ||||||||||||
| Control | 39 | 0.72 | 0.15 | N/A | 40 | 0.62* | 0.06 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 38 | 0.67 | 0.13 | 0.15 | 37 | 0.62* | 0.07 | 0.94 | -0.04 | (-0.11-0.02) | 0.29 | 0.94 |
| G:I ratio h | ||||||||||||
| Control | 39 | 345.08 | 219 | N/A | 39 | 186.01* | 49.14 | N/A | N/A | N/A | N/A | 1.00 |
| BV | 36 | 271 | 194 | 0.11 | 36 | 185.23* | 79.07 | 0.92 | 0.15 | (-0.05-0.35) | 0.28 | 0.78 |
All data are expressed in geometric mean ± S.D.. N/A: not applied to this model.
Paired t-test was performed to compare within changes in intervention group during the study.
Independent sample t-test was performed between group.
Repeated measure of ANOVA was carried out in the main effect of model.
Homeostatic model assessment.
Assessment of B-cell functionality.
quantitative insulin sensitivity check index glucose to insulin ratio.
Glucose to insulin ratio.