Table 1.
Immunostaining Score of HKDC1 Expression for Different Organs.
| Tissue | Intensity | Distribution | Summary Score |
|---|---|---|---|
| 1. Esophageal squamous mucosa | |||
| a. Basal layer | 1 | 3 | 3 |
| b. Suprabasal squamous epithelium | 2 | 3 | 6 |
| 2. Stomach | |||
| a. Superficial foveolar epithelium | 2 | 3 | 6 |
| b. Parietal cells and chief cells | 3 | 3 | 9 |
| 3. Small intestine | |||
| a. Villous brush border | 3 | 3 | 9 |
| b. Deep crypt epithelium | 0 | 3 | 0 |
| 4. Colon | |||
| a. Surface epithelium | 3 | 3 | 9 |
| b. Crypt base epithelium | 1 | 2 | 2 |
| 5. Muscularis propria of GI tract | |||
| a. Smooth muscle | 2 | 3 | 6 |
| b. Myenteric plexus: | |||
| Focal | 3 | 1 | 3 |
| Rest | 1 | 3 | 3 |
| 6. Pancreas | |||
| a. Acinar cells | 0 | 3 | 0 |
| b. Acinar centrocytes | 3 | 3 | 9 |
| c. Interlobular pancreatic duct | 3 | 3 | 9 |
| d. Larger pancreatic duct | 3 | 3 | 9 |
| e. Pancreatic islet cells | 1 | 1 | 1 |
| 7. Liver | |||
| a. Hepatocytes | 0 | 3 | 0 |
| b. Interlobular bile duct | 1 | 1 | 1 |
| 8. Spleen | |||
| a. Red pulp | 1 | 3 | 3 |
| b. White pulp | 1–2 | 1 | 1–2 |
| 9. Adipose tissue | 0–1 | 3 | 0–3 |
| 10. Cardiac muscle | |||
| a. 90% cardiomyocytes | 1 | 3 | 3 |
| b. 10% cardiomyocytes | 2 | 1 | 2 |
| 11. Skin | |||
| a. Epidermis | 1 | 1 | 1 |
| b. Sebaceous gland | 0 | 3 | 0 |
| c. Hair follicle | 1 | 3 | 3 |
| d. Sweat glands | 1 | 3 | 3 |
| e. Sweat gland duct | 2 | 3 | 6 |
| 12. Kidney | |||
| a. Renal tubule | |||
| 90% cells | 1 | 3 | 3 |
| 10% cells | 2 | 1 | 2 |
| Glomerulus | 1 | 1 | 1 |
| 13. Lung | |||
| a. Alveolar lining cells | 1 | 3 | 3 |
| b. Alveolar macrophages | 3 | 3 | 9 |
| c. Bronchial epithelium | 2 | 3 | 6 |
| 14. Prostate | |||
| a. Basal cells | 2 | 3 | 6 |
| b. Gland epithelium | 1 | 3 | 3 |
| c. Stromal cells | 1–2 | 3 | 3–6 |
| 15. Skeletal muscle | 1 | 3 | 3 |
| 16. Testes | 1 | 2 | 3 |
| 17. Thyroid | 2–3 | 3 | 6–9 |
Abbreviations: HKDC1, hexokinase domain containing 1; GI = gastrointestinal.