Figure 1.

(A) Sequences of human and mouse neutrophil-activating chemokines. Conserved basic residues implicated in heparin interactions are highlighted in red and shaded in gray. Chemokine-specific residues that have been shown to be involved in heparin binding are in bold blue and underlined. Quasi-conserved residues are shown in red. (B) Table showing conserved residues that are involved in heparin binding from NMR studies. Abbreviation: NMR, nuclear magnetic resonance.