Figure 3.
Salmonella infection protocol timeline. The course of events detail administration of HA35 (300 µg once daily) or water 3 days before, and continuing throughout Salmonella enterica serovar Typhimurium strain SL1344 infection (1 × 108 on day 1) in c57Bl/6 mice (n=5). Streptomycin (20 µg) is provided 24 hr before infection (day −1). All tissue collection, homogenization, and plating occur on day 4 with direct plate colony counts (cfu) recorded on day 5. Abbreviation: HA35, 35 kDa hyaluronan.