Table 3.

Cox proportional hazard models of recurrence-free and overall survival among the retrospective stage III cohort

		Univariate Hazard Model
		Recurrence-Free Survival			Overall Survival
		HR	95% CI	P-value	HR	95% CI	P-value
NY-ESO-1 Vaccine		0.555	(0.374, 0.822)	0.0034	0.507	(0.310, 0.831)	0.007
Thickness (1 mm)		1.079	(1.044, 1.116)	< 0.0001	1.101	(1.062, 1.141)	< 0.0001
Ulceration	Absent	1			1
	Present	2.206	(1.490, 3.266)	< 0.0001	2.185	(1.336, 3.573)	0.0019
	Undetermined	1.079	(0.600, 1.940)	0.8002	0.953	(0.413, 2.196)	0.9093
Age (1 year)		1.015	(1.002, 1.027)	0.0201	1.025	(1.008, 1.042)	0.0033
AJCC Stage	IIIA	1			1
	IIIB	1.141	(0.730, 1.783)	0.5627	1.005	(0.643, 1.570)	0.9842
	IIIC	1.795	(1.130, 2.850)	0.0132	1.457	(0.915, 2.319)	0.1129
		Multivariate Hazard Model
		Recurrence-Free Survival			Overall Survival
		HR	95% CI	P-value	HR	95% CI	P-value
NY-ESO-1 Vaccine		0.454	(0.301, 0.685)	0.0002	0.403	(0.269, 0.604)	< 0.0001
AJCC Stage	IIIA	1	(0.561, 1.370)		1
	IIIB	1.225	(0.783, 1.916)	0.3744	1.028	(0.658, 1.608)	0.9026
	IIIC	2.348	(1.452, 3.797)	0.0005	1.792	(1.114, 2.883)	0.0161