Table/Fig-5.
Summary of organisms used and the observed results of inhibition by compound.
| Bacterium | Gram Reaction | Positive Control | Fc-Br | Fc-Cl | Fc-F | Fc-I | Fc-Ph | Fc-Py |
|---|---|---|---|---|---|---|---|---|
| S. aureus | + | Penicillin | − | − | − | − | − | − |
| E. coli | − | Kanamycin | − | − | − | − | − | − |
| M. luteus | + | Penicillin | + I |
+ I |
− | − | − | − |
| P. aeruginosa | − | Kanamycin | − | − I, II, III NP |
− | − I, II, III NP |
− | − |
| S. marcescens | − | Kanamycin | − | − | − | − | N/A | − |
| K. pneumoniae | − | Kanamycin | − | − | − | − | N/A | − |
| B. subtilis | + | Kanamycin | + I, II, III |
+ I, II, III |
+ I |
+ I, II, III |
N/A | − |
| P. vulgaris | − | Kanamycin | − | − | − | − | N/A | − |
| E. aerogenes | − | Kanamycin | − | − | − | − | N/A | − |
4-fluorophenyl ferrocenecarboxylate (Fc-4F-Ph), 4-chlorophenyl ferrocenecarboxylate (Fc-4-Cl-Ph), 4-bromophenyl ferrocenecarboxylate (Fc-4Br-Ph), 4-iodophenyl ferrocenecarboxylate (Fc-4I-Ph), and their analog replacing the halide with a redox active specie 4-(1H-pyrrol-1-yl)-phenylferrocenecarboxylate (Fc-Py). Bacteria, gram-staining, antibiotic controls and concentrations (I: concentration I; II: concentration II; III: concentration III) used of ferrocenecarboxylates, with corresponding outcome.
(−): No inhibition observed; (+): Inhibition observed; NP: No pigmentation; N/A: not assayed