Table II.
The mutation rates in the recruited groups (n=437).
| Recruit Criteria | N | BRCA+a (%) | P-value |
|---|---|---|---|
| EOb | 173 | 16 (9.2) | |
| BC/OC FH | 129 | 28 (21.7) | |
| BBC | 50 | 12 (24.0) | |
| MBC | 9 | 2 (22.2) | 0.007 |
| BC&OC | 6 | 1 (16.7) | |
| Fixed | 70 | 17 (24.3) | |
| Total | 437 | 76 (17.4) |
EO, early-onset breast cancer; BC/OC FH, breast and/or ovarian cancer family history; BBC, bilateral breast cancer; MBC, male breast cancer; BC&OC, breast cancer with ovarian cancer.
a
Both BRCA1 and BRCA2 mutations.
b
Patients were diagnoses with BC onset breast cancer, BC/OC FH, breast and/or ovarian cancer family history; BBC, bilateral breast cancer.