Table VII.

Familial mutations information (n=11).

Gene	Location	Family history features	Chinesea
BRCA1	c.190T>Cb	HBOC of maternal hereditary	N
	c.1660G>T	BC sisters	Y
	c.2014A>T	BCs of maternal history	N
	c.212+G>T	BCs of maternal history	Y
	c.3640G>T	BC sisters	N
	c.5431C>T	HBOC of paternal hereditary	N
BRCA2	c.988del	BC sisters	N (Novel)
	c.1310_1313del	BCs maternal history	N
	c.5753del	BCs maternal history	N (Novel)
	c.6288_6289del	BCs maternal history	N (Novel)
	c.9090dupb	Paternal line	N (Novel)

BC, breast cancer; HBOC, heredity breast and ovarian cancer syndrome family; Y, yes; N, no.

^aWhether mutation was once reported in Chinese.

^bCarried by the same proband.