Figure 4.

EZH2 knockdown inhibited the endometrial cancer cells invasion. (A) si-EZH2 and si-control cell lines were assayed for invasion by control and Matrigel-coated Transwell. The results were quantified by manual counting. **P<0.01 vs. the si-control group. (B) The markers of epithelial-mesenchymal transition were detected by western blot analysis (left) and RT-qPCR (right). A representative blot was shown from 3 independent experiments. EZH2, enhancer of zeste homolog 2; RT-qPCR, quantitative reverse transcription-polymerase chain reaction; si, small interfering; E-, epithelial-; N-, neural-; ZEB, zinc finger E-box binding homeobox.