Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 10;15(6):4629–4636. doi: 10.3892/etm.2018.6049

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Lu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Overexpression of HO-1 via recombinant adenovirus transfection ameliorated post-ischemic neuronal apoptosis induced by secondary brain damage in transient cerebral ischemia-reperfusion injury. (A and B) Transfection of HO-1 gene caused significantly increased HO-1 protein expression levels in the cerebral cortex of rats compared with that in the vehicle and Ad groups. Furthermore, overexpression of HO-1 significantly enhanced the anti-apoptotic effect as determined by (C) terminal deoxynucleotidyl-transferase-mediated dUTP nick end staining and (D) caspase-3 activity. Data are presented as the mean ± standard deviation (repeats, n=6). *P<0.05 vs. vehicle and Ad-HO-1 groups and **P<0.01 vs. sham group. Ad, empty adenovirus vector group; HO-1, heme oxygenase-1; Ad-HO-1, recombinant HO-1 adenovirus.