Table I.
Cimetidine (mg/kg) | ||||
---|---|---|---|---|
Organ | Control | 20 | 40 | 120 |
Testis | ||||
(g) | 3.384±0.173 | 3.516±0.337 | 3.445±0.269 | 3.466±0.231 |
(g/100 g b.w.) | 0.601±0.067 | 0.633±0.049 | 0.630±0.074 | 0.628±0.022 |
Epididymis | ||||
(g) | 1.298±0.080 | 1.264±0.105 | 1.281±0.100 | 1.274±0.119 |
(g/100 g b.w.) | 0.231±0.024 | 0.229±0.025 | 0.234±0.027 | 0.230±0.011 |
Preputial gland | ||||
(g) | 0.091±0.015 | 0.092±0.024 | 0.108±0.028 | 0.099±0.018 |
(g/100 g b.w.) | 0.016±0.003 | 0.017±0.005 | 0.020±0.005 | 0.018±0.003 |
Prostate gland | ||||
(g) | 1.495±0.161 | 1.582±0.197 | 1.579±0.178 | 1.542±0.275 |
(g/100 g b.w.) | 0.266±0.043 | 0.285±0.030 | 0.287±0.024 | 0.278±0.040 |
Seminal vesicle | ||||
(g) | 1.724±0.135 | 1.729±0.296 | 1.856±0.209 | 2.020±0.273a |
(g/100 g b.w.) | 0.307±0.038 | 0.315±0.072 | 0.338±0.033 | 0.368±0.061 |
Levator ani muscle | ||||
(g) | 0.317±0.048 | 0.310±0.033 | 0.292±0.038 | 0.310±0.036 |
(g/100 g b.w.) | 0.056±0.008 | 0.056±0.006 | 0.053±0.008 | 0.056±0.006 |
Sphincter ani | ||||
(g) | 1.167±0.084 | 1.169±0.134 | 1.171±0.107 | 1.141±0.113 |
(g/100 g b.w.) | 0.207±0.018 | 0.212±0.034 | 0.214±0.021 | 0.207±0.015 |
P<0.05 vs. control group. Values are expressed as the mean ± standard deviation (n=8). b.w., body weight.