Table III.

Expression of COX-2, iNOS and NF-κB, and apoptosis in testis of male rats.

		Cimetidine (mg/kg)
Protein/item	Control	20	40	60
COX-2	0.167±0.011	0.169±0.013	0.172±0.006	0.192±0.009a
iNOS	0.312±0.020	0.341±0.009a	0.334±0.005a	0.358±0.011b
NF-κB	0.333±0.010	0.330±0.011	0.338±0.021	0.355±0.008a
Apoptosis	0.327±0.016	0.319±0.022	0.331±0.019	0.363±0.013b

^aP<0.05

^bP<0.01 vs. control group. Values are expressed as the mean ± standard deviation (n=8). iNOS, inducible nitric oxide synthase; NF, nuclear factor; COX, cyclooxygenase.