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. 2018 Apr 12;15(6):8935–8940. doi: 10.3892/ol.2018.8477

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — PGAM1 immunohistochemical staining in peritumoral brain tissue and diffuse astrocytoma (WHO grade II). (A) Hematoxylin and eosin stain of peritumoral brain tissue. Magnification, ×400. (B) Peritumoral brain tissue is negative for PGAM1. Magnification, ×400. (C) Hematoxylin and eosin stain demonstrates brain tissue infiltrated by mildly hypercellular glial cells with irregular and atypical nuclei and inconspicuous mitotic activity, diagnostic of diffuse astrocytoma (WHO grade II). Magnification, ×200. (D) Diffuse astrocytoma is positive for PGAM1 with a cytoplasmic staining pattern. Magnification, ×200. PGAM1, phosphoglycerate mutase 1.