Figure 4.

Effects of miR-3160-5P on cell cycle regulator expression in DU145 cells. (A) The expression of cell cycle regulators was analyzed by western blot analysis. (B) The intensities of the bands relevant to p-CDC2, total CDC-2, CDC25C, cyclin B1 and Fbxw8 protein were normalized to that of β-actin. Representative results of three experiments are presented as the mean ± standard deviation. *P<0.05 vs. miR-SCR. miR, microRNA; CDC, cell division cycle; Fbxw8, F-box and WD repeat domain containing 8; miR-SCR, scramble microRNA.