Table I.
Clinical characteristics of ALK-positive patients.
| Characteristic | n |
|---|---|
| Total | 22 (ALK-positive) |
| Sex | |
| Male | 8 |
| Female | 14 |
| Age, years | 32–82 (mean, 58.5) |
| Smoking status | |
| Yes | 8 |
| No | 14 |
| Histological subtype | 21 adenocarcinoma (21 mucinous carcinoma), 1 undifferentiated carcinoma |
| Metastasis | |
| Yes | 20 |
| No | 2 |
| Chemo- or radiation therapy | |
| Yes | 22 |
| No | 0 |
| Additional crizotinib treatment | |
| Yes | 15 |
| No | 7 |
| Current disease status | |
| Complete response | 0 |
| Stable disease | 8 |
| Partial response | 3 |
| Progressive disease | 11 |
In total, 23 patients were analyzed (22 patients were ALK-positive, and 1 patient was ALK-negative).