Western blot analysis. Level of (A) COX-2, (B) PGE2 and (C) VEGF expression in MCF-7 cells treated with ketamine, propofol and celecoxib at a dose of 180 µmol/l. Data are presented as the mean ± standard deviation of experiments performed in triplicate. *P<0.05 vs. ketamine group. 1, ketamine; 2, propofol; 3, celecoxib; COX-2, cyclooxygenase-2; PGE2, prostaglandin E2; VEGF, vascular endothelial growth factor.