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. 2018 Apr 17;15(6):9543–9552. doi: 10.3892/ol.2018.8513

Figure 1.

Figure 1.

lncRNA BANCR expression is upregulated in BC cells and tissues, which is associated with poor prognosis of patients with BC. (A) The expression of BANCR was detected via RT-qPCR in normal human breast epithelial cell line, MCF10A, noninvasive BC cell lines (MDA-MB-468, MCF7 and HCC1569) and invasive BC cell lines (BT549 and MDA-MB-231). (B) The expression of BANCR in non-cancerous tissues and BC tissues was verified by RT-qPCR. (C) The Kaplan-Meier method and log-rank test were utilized to analyze the difference in OS rate between the low- and high-BANCR-expression groups. (D) The Kaplan-Meier method and log-rank test were used to analyze the difference in RFS rate between the low- and high-BANCR-expression groups. Statistical significance was determined using Student's t-test between indicated columns in (A and B), and by log-rank test in (C and D). *P<0.05, **P<0.01. BC, breast cancer; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; BANCR, BRAF-regulated lncRNA 1; OS, overall survival; RFS, recurrence-free survival.