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CCT3 knockdown induces apoptosis. (A) Apoptosis was determined by Annexin V staining followed by flow cytometry. Region R3 spans the fluorescence density of apoptotic cells. Representative images for each group are shown. (B) Quantification of results shown in (A) (n=3). ***P<0.001, shCtrl vs. shCCT3. CCT3, chaperonin containing TCP1 subunit 3; shCtrl, control short hairpin RNA.
