Table I.
Association between EHMT1 expression and clinicopathological factors of gastric cancer patients.
| EHMT1 protein expression | ||||
|---|---|---|---|---|
| Clinicopathological factor | n | Positive (n=65) | Negative (n=32) | P-value |
| Sex | 0.420 | |||
| Male | 74 | 48 | 26 | |
| Female | 23 | 17 | 6 | |
| Age, years | 0.497 | |||
| ≥60 | 59 | 38 | 21 | |
| <60 | 38 | 27 | 11 | |
| Tumor differentiation | 0.517 | |||
| Well to moderate | 38 | 24 | 14 | |
| Poor | 59 | 41 | 18 | |
| Tumor location | 0.295 | |||
| Gastric fundus | 3 | 1 | 2 | |
| Gastric corpus | 41 | 30 | 11 | |
| Pylorus | 53 | 34 | 19 | |
| Tumor size, cm | 0.430 | |||
| ≤3 | 46 | 29 | 17 | |
| >3 | 51 | 36 | 15 | |
| Tumor stage | 0.033 | |||
| T1-T2 | 37 | 20 | 17 | |
| T3-T4 | 60 | 45 | 15 | |
| Lymph node metastasis | 0.003 | |||
| Negative | 43 | 22 | 21 | |
| Positive | 54 | 43 | 11 | |
| Distant metastasis | 0.316 | |||
| Negative | 95 | 63 | 32 | |
| Positive | 2 | 2 | 0 | |
| TNM stage | 0.837 | |||
| I+II | 38 | 25 | 13 | |
| III+IV | 59 | 40 | 19 | |
Positive EHMT1 expression includes all positive cases, including weak and strong staining. EHMT1, euchromatic histone lysine methyltransferase 1; TNM, tumor-node-metastasis.