Table I.
Analyses of E2Fs in breast cancer.
| Gene symbol | Dataset | Reporter | Normal (no. of cases) | Tumor (no. of cases) | Fold-change | T-value | P-value |
|---|---|---|---|---|---|---|---|
| E2F1 | TCGA Breast | A_23_P80032 | Breast (61) | Invasive breast carcinoma (76) | 2.734 | 11.690 | 1.68×10−22 |
| A_23_P80032 | Breast (61) | Invasive ductal breast carcinoma (389) | 3.216 | 18.607 | 4.37×10−35 | ||
| A_23_P80032 | Breast (61) | Invasive lobular breast carcinoma (36) | 2.088 | 6.425 | 1.56×10−8 | ||
| Gluck Breast | 26634 | Breast (4) | Invasive breast carcinoma (154) | 2.545 | 10.681 | 2.29×10−5 | |
| E2F2 | Curtis Breast | ILMN_1777233 | Breast (144) | Medullary breast carcinoma (32) | 5.025 | 14.502 | 1.28×10−16 |
| ILMN_1777233 | Breast (144) | Invasive ductal breast carcinoma (1,556) | 2.767 | 33.780 | 3.89×10−93 | ||
| ILMN_1777233 | Breast (144) | Invasive breast carcinoma (21) | 2.315 | 6.844 | 3.56×10−7 | ||
| Gluck Breast | 20301 | Breast (4) | Invasive breast carcinoma (154) | 2.637 | 11.788 | 7.06×10−7 | |
| TCGA Breast | A_23_P408957 | Breast (61) | Invasive ductal breast carcinoma (389) | 3.790 | 18.457 | 7.38×10−35 | |
| A_23_P408957 | Breast (61) | Invasive breast carcinoma (76) | 3.094 | 11.308 | 1.62×10−21 | ||
| A_23_P408955 | Breast (61) | Invasive lobular breast carcinoma (36) | 2.243 | 7.520 | 6.13×10−11 | ||
| Zhao Breast | IMAGE: 293331 | Breast (3) | Invasive ductal breast carcinoma (37) | 2.222 | 6.084 | 7.11×10−6 | |
| Richardson Breast 2 | 228361_at | Breast (7) | Ductal breast carcinoma (40) | 3.077 | 6.237 | 5.25×10−5 | |
| E2F3 | Curtis Breast | ILMN_1669502 | Breast (144) | Medullary breast carcinoma (32) | 2.522 | 11.118 | 2.89×10−13 |
| Richardson Breast 2 | 203692_s_at | Breast (7) | Ductal breast carcinoma (40) | 3.558 | 8.624 | 9.00×10−9 | |
| E2F4 | Not available | ||||||
| E2F5 | Richardson Breast 2 | 221586_s_at | Breast (7) | Ductal breast carcinoma (40) | 2.573 | 6.253 | 9.00×10−8 |
| TCGA Breast | A_23_P31713 | Breast (61) | Invasive breast carcinoma (76) | 2.077 | 7.228 | 1.75×10−11 | |
| E2F6 | Not available | ||||||
| E2F7 | Richardson Breast 2 | 228033_s_at | Breast (7) | Ductal breast carcinoma (40) | 4.535 | 7.879 | 4.65×10−10 |
| TCGA Breast | A_23_P336178 | Breast (61) | Invasive breast carcinoma (76) | 5.193 | 12.912 | 1.43×10−25 | |
| A_23_P336178 | Breast (61) | Invasive ductal breast carcinoma (389) | 7.456 | 22.097 | 5.96×10−40 | ||
| A_23_P336178 | Breast (61) | Invasive lobular breast carcinoma (36) | 4.262 | 9.860 | 8.61×10−15 | ||
| E2F8 | Gluck Breast | 20493 | Breast (4) | Invasive breast carcinoma (154) | 2.489 | 13.421 | 4.37×10−6 |
| TCGA Breast | A_23_P35871 | Breast (61) | Invasive lobular breast carcinoma (36) | 5.188 | 9.033 | 2.05×10−14 | |
| A_23_P35871 | Breast (61) | Invasive breast carcinoma (76) | 7.581 | 11.979 | 5.70×10−23 | ||
| NM_024680_1_1600 | Breast (61) | Invasive ductal breast carcinoma (389) | 2.416 | 17.311 | 2.20×10−34 |
a
P<0.05. TCGA, The Cancer Genome Atlas.