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Association of protein expression of HMGB1, BRCA1 and P62 with drug-resistance to cisplatin in ovarian cancer.
| HMGB1 | BRCA1 | P62 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Groups | No. | Positive | Positive rate | P-value | Positive | Positive rate | P-value | Positive | Positive rate | P-value |
| Drug resistance | 38 | 32 | 84.21% | <0.01 | 36 | 94.74% | <0.01 | 35 | 92.11% | <0.01 |
| Sensitive | 22 | 5 | 22.73% | <0.01 | 11 | 50.00% | <0.01 | 8 | 36.36% | <0.01 |
HMGB1, high mobility group box 1; BRCA1, breast cancer susceptibility gene 1.
