Table I.
GO and KEGG enrichment analyses of the DEGs in uLMS.
| Category | Term | Count | P-value |
|---|---|---|---|
| Upregulated | |||
| GOTERM_BP_FAT | GO:0006259~DNA metabolic process | 5 | 6.93E-03 |
| GOTERM_BP_FAT | GO:0034654~nucleobase-containing compound biosynthetic process | 9 | 7.24E-03 |
| GOTERM_BP_FAT | GO:0034645~cellular macromolecule biosynthetic process | 10 | 7.48E-03 |
| GOTERM_CC_FAT | GO:0000307~cyclin-dependent protein kinase holoenzyme complex | 2 | 3.57E-02 |
| GOTERM_MF_FAT | GO:0001135~transcription factor activity, RNA polymerase II transcription factor recruiting | 2 | 8.53E-03 |
| GOTERM_MF_FAT | GO:0001134~transcription factor activity, transcription factor recruiting | 2 | 1.10E-02 |
| GOTERM_MF_FAT | GO:0016538~cyclin-dependent protein serine/threonine kinase regulator activity | 2 | 2.66E-02 |
| Downregulated | |||
| GOTERM_BP_FAT | GO:0070887~cellular response to chemical stimulus | 26 | 7.35E-09 |
| GOTERM_BP_FAT | GO:0006928~movement of cell or subcellular component | 21 | 2.66E-07 |
| GOTERM_BP_FAT | GO:0010035~response to inorganic substance | 10 | 4.83E-07 |
| GOTERM_CC_FAT | GO:0042383~sarcolemma | 5 | 1.75E-04 |
| GOTERM_CC_FAT | GO:0098590~plasma membrane region | 10 | 2.40E-04 |
| GOTERM_CC_FAT | GO:0005887~integral component of plasma membrane | 13 | 1.23E-03 |
| GOTERM_MF_FAT | GO:0005267~potassium channel activity | 5 | 1.32E-03 |
| GOTERM_MF_FAT | GO:0015079~potassium ion transmembrane transporter activity | 5 | 2.11E-03 |
| GOTERM_MF_FAT | GO:0015269~calcium-activated potassium channel activity | 3 | 2.41E-03 |
| KEGG_PATHWAY | ptr05202: Transcriptional misregulation in cancer | 7 | 5.69E-04 |
| KEGG_PATHWAY | ptr05205: Proteoglycans in cancer | 6 | 7.61E-03 |
| KEGG_PATHWAY | ptr05200: Pathways in cancer | 7 | 3.23E-02 |
GO, Gene Ontology; KEGG, Kyoto Encyclopaedia of Genes and Genomes; DEGs, differentially expressed genes; uLMS, uterine leiomyosarcoma.