Table III.
GO and KEGG enrichment analyses of genes in the significant module of the PPI network.
| Category | Term | Count | P-value | Genes |
|---|---|---|---|---|
| GOTERM_BP_FAT | GO:0016477~cell migration | 5 | 1.23E-05 | SDC1, APOE, IGF1, THBS1, CXCL12 |
| GOTERM_BP_FAT | GO:0048870~cell motility | 5 | 1.93E-05 | SDC1, APOE, IGF1, THBS1, CXCL12 |
| GOTERM_BP_FAT | GO:0051674~localization of cell | 5 | 1.93E-05 | SDC1, APOE, IGF1, THBS1, CXCL12 |
| GOTERM_CC_FAT | GO:0009897~external side of plasma membrane | 3 | 1.23E-03 | SDC1, THBS1, CXCL12 |
| GOTERM_CC_FAT | GO:0031988~membrane-bounded vesicle | 5 | 2.18E-03 | SDC1, APOE, IGF1, THBS1, CXCL12 |
| GOTERM_CC_FAT | GO:0098552~side of membrane | 3 | 3.63E-03 | SDC1, THBS1, CXCL12 |
| GOTERM_MF_FAT | GO:0071813~lipoprotein particle binding | 2 | 4.77E-03 | APOE, THBS1 |
| GOTERM_MF_FAT | GO:0071814~protein-lipid complex binding | 2 | 4.77E-03 | APOE, THBS1 |
| GOTERM_MF_FAT | GO:0005102~receptor binding | 3 | 1.05E-02 | APOE, IGF1, CXCL12 |
| KEGG_PATHWAY | ssc05205: Proteoglycans in cancer | 3 | 4.21E-03 | SDC1, IGF1, THBS1 |
| KEGG_PATHWAY | ssc05144: Malaria | 2 | 2.93E-02 | SDC1, THBS1 |
| KEGG_PATHWAY | ssc04115: p53 signaling pathway | 2 | 4.04E-02 | IGF1, THBS1 |
| KEGG_PATHWAY | ssc04512: ECM-receptor interaction | 2 | 4.53E-02 | SDC1, THBS1 |
GO, Gene Ontology; KEGG, Kyoto Encyclopaedia of Genes and Genomes; PPI, protein-protein interaction.