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Bcl-2 induces the metastasis of BCap37 cells to the lung in vivo. BCap37, BC-Mock BC-Bcl2, BC-shRNA-NC or BC-shRNA-Bcl2 cells were implanted into the right flanks of homozygous nude athymic mice (n=5 for each group). (A) Representative micrographs (magnification, ×200) and (B) results of histopathological analyses of lung tissues from each group, 30 days post-implantation. ***P<0.001. BC, BCap37 cell; Bcl-2, B-cell lymphoma 2; shRNA, short hairpin RNA; NC, negative control.
