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. 2018 Mar 27;53(1):59–72. doi: 10.3892/ijo.2018.4333

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Copyright: © Pan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Overexpression of MORC2 promotes migration, invasion and motility of SMMC7721 cells in vitro. (A) Cell migration was assessed using a Transwell assay in SMMC7721^MORC2 and SMMC7721^vector cells; the cells that migrated to the bottom surface of the filters were stained. Magnification, ×100. (B) Cell invasion was assessed using a Transwell assay with Matrigel in SMMC7721^MORC2 and SMMC7721^vector cells; cells, which migrated to the bottom surface of the filters, were stained. Magnification, ×100. (C) Movement ability was detected using scratch wound healing assays in SMMC7721^MORC2 and SMMC7721^vector cells. Magnification, ×40. Date are presented as the mean ± standard deviation of three or six independent experiments. ^***P<0.001. MORC2, microrchidia; CON, control.