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Treatment scenarios simulated in this study with a system that integrates PK-PD intracellular multi-compartment models with a vascularized tumor growth model.
| Scenario | Chemotherapy Description |
|---|---|
| Case 1 | MTD for both cisplatin and gemcitabine |
| Case 2 | Metronomic cisplatin and gemcitabine at MTD |
| Case 3 | Cisplatin at MTD and metronomic gemcitabine |
| Case 4 | Metronomic for both cisplatin and gemcitabine |
