Table 1.
Patient descriptive characteristics by treatment group, values presented are mean (SD) or N (%) where indicated.
| Covariate | Overall (N=28) | Topiramate Only (N=11) |
|---|---|---|
| Female | 20 (71.4%) | 8 (72.7%) |
| Age (years) | 15.2 (2.5) | 14.5 (2.8) |
| Height (cm) | 164 (9.6) | 162 (8.3) |
| Weight (kg) | 126 (35.0) | 128 (45.8) |
| BMI (kg/m2) | 46.2 (10.3) | 47.6 (13.8) |
| BMI z-score | 2.68 (0.33) | 2.74 (0.38) |
| Tanner Stage | ||
| - Tanner III | 4 (14.3%) | 1 (9.1%) |
| - Tanner IV | 5 (17.9%) | 2 (18.2%) |
| - Tanner V | 6 (21.4%) | 4 (36.4%) |
| - Missing Tanner | 13 (46.4%) | 4 (36.4%) |
| Topiramate Dose | ||
| - 25 mg | 1 (3.6%) | 0 (0.0%) |
| - 50 mg | 2 (7.1%) | 1 (9.1%) |
| - 75 mg | 23 (82.1%) | 10 (90.9%) |
| - 100 mg | 1 (3.6%) | 0 (0.0%) |
| - 125 mg | 1 (3.6%) | 0 (0.0%) |
| Mean Topiramate Dose (mg) | 74.1 (15.9) | 75.0 (19.8) |
| SBP (mmHg) | 126 (15.6) | 124 (16.4) |
| DBP (mmHg) | 72.6 (13.8) | 74.2 (16.0) |
| HR (bpm) | 86.2 (15.7) | 83.1 (14.2) |