Fig. 5.

(A) Bubble expansion rate over the course of a shock-scattering histotripsy pulse based on the numerical integration of the Yang/Church model (dashed line) and the analytic prediction via (9) (crosses). The peak positive/peak negative pressures were 98.8/15.8 MPa for the brown symbols, 102.8/16.9 MPa for the yellow symbols, and 107/18.3 MPa for the blue symbols. (B) Predicted axial extent of the bubble cloud initiated with a 5-μs shock-scattering histotripsy pulse as a function of the elastic modulus of the medium. The fundamental frequency of the shock scattering pulse was 1 MHz. Kelvin-Voight elasticity was used in the calculation.