Fig. 8.

Elevated t-DARPP, NF-ĸB2 and IKKα transcripts correlate with decreased lung adenocarcinoma patient survival. a Quantification of t-DARPP mRNA expression in 513 human lung cancer tissue samples. Blue dots indicate outliers. T1–T4 represents tumor (T) staging scores from TNM system. b Kaplan–Meier plot showing overall survival within the total cohort of 513 NSCLC patients based on the expression of t-DARPP and DARPP-32 mRNAs. c Kaplan–Meier curve depicting overall survival within the total cohort of 201 NSCLC patients based on the expression of NF-ĸB2 or d IKKα mRNAs. The normalized read count for DARPP-32, t-DARPP, NF-ĸB2 and IKKα mRNAs were obtained from The Cancer Genome Atlas dataset (TCGA). The difference between the two groups was calculated using log-rank (Mantel–Cox) test. HR hazard ratio