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. Author manuscript; available in PMC: 2018 May 18.
Published in final edited form as: React Oxyg Species (Apex). 2016 Mar;1(2):141–156. doi: 10.20455/ros.2016.829

FIGURE 4. Schematic illustration of the molecular and cellular pathways involved in high-dose vitamin C-mediated selective cytotoxicity to cancer cells that both overexpress GLUT1 and have become addicted to glycolysis for energy production.

FIGURE 4

GAP and BPG denote glyceraldehyde 3-phosphate and 1,3-bisphosphoglycerate, respectively. This scheme is based on Ref. [4].