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. Author manuscript; available in PMC: 2018 May 18.
Published in final edited form as: Neurosci Lett. 2018 Feb 2;670:89–93. doi: 10.1016/j.neulet.2018.01.043

Fig. 3.

Fig. 3

Celastrol supports RGC survival from ocular hypertension damage. A. Rbpms-positive RGCs in flat mounted retinas from vehicle- and celastrol-treated animals with normal and elevated IOP. Images represent temporal retinal quadrants. B. A repeated measures ANOVA was conducted to compare RGC density in vehicle-treated, celastrol-treated, vehicle-treated with IOP elevation, and celastrol-treated with IOP elevation groups after controlling for the quadrant and distance effects. A significant decrease of RGC density was observed in Vehicle/ IOP compared to Vehicle group (*P = 0.0078). There was a significant increase of RGC density in Celastrol/IOP compared to Vehicle/IOP group (**P = 0.021). Data are presented as mean ± SD.