Table 1. Candidate genes for knockdown (those targeted in this study are in bold).
Gene | Viral life cycle target |
---|---|
ATP6AP1 | vATPase complex |
ATP6AP2 | |
ATP6V0C | |
ATP6V0D1 | |
ATP6V1A | |
ATP6V1B2 | |
COPA | COPI proteins |
COPB2 | |
COPG | |
ARCN1 | |
KPNB1 | nucleo-cytoplasmic transport factors |
NUP98 | |
NXF1 | |
CLK1 | splicing machinery |
PRPF8 | |
SF3B1 | |
SNRP70 | |
RPS14 | virus-specific translation |
RPS5 | |
RPS10 | |
RPS16 | |
B2M | miscellaneous/unknown |
BARHL2 | |
BZRAP1 | |
ISG15 | |
JUN | |
MYC | |
PPP1R14D | |
PSENEN | |
PTPRN | |
TNK2 | |
MAP2K3 | |
PGD |
Thirty-three candidate genes meeting the selection criteria outlined in Methods are grouped by their role and location in the viral life cycle. Genes selected for evaluation in this study are shown in bold.