Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun;24(6):865–879. doi: 10.1261/rna.063206.117

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Hönig et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

FIGURE 2. — The miR-29 family members can be targeted in mouse pups directly injected with an antimiR. Either a scrambled antimiR (open symbols) or an antimiR directed against miR-29a-3p (closed symbols) was administered by intraperitoneal injection (25 mg kg⁻¹) to newborn mouse pups on the day of birth. Organs were harvested from mouse pups on the seventh day of life: (B) brain, (H) heart, (K) kidney, (Li) liver, (Lu) lung. Total RNA pools were screened by real-time RT-PCR for (A) miR-29a-3p, (B) miR-29a-5p, (C) miR-29b-3p, and (D) miR-29c-3p. The miR steady-state expression levels are described by the mean ΔCT ± SD. (n = 5–6 animals, per group; each symbol represents an individual animal), where ΔCT = CT_(Rnu6) − CT_{(miR of interest)}. Mean values were compared between the scrambled versus miR-29a-3p-specific antimiR-treated mouse pups by unpaired Student's t-test. (*) P < 0.05; (***) P < 0.001; (****) P < 0.0001.