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. 2018 Jun;24(6):865–879. doi: 10.1261/rna.063206.117

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© 2018 Hönig et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 5. — Maternal and direct administration of antimiR-29a-3p did impact postnatal growth of mouse pups. The body mass of mouse pups delivered by dams treated with intraperitoneal (i.p.) or intravenous (i.v.) scrambled antimiR (open circles) or antimiR-29a-3p (closed circles) was assessed on (A) the day of birth, postnatal day (P)1; as well as on (B) P7 and (C) P14. Additionally, the body mass of mouse pups directly injected at P1 (via the i.p. route) with scrambled antimiR (open circles) or antimiR-29a-3p (closed circles) was also assessed at (B) P7 and (C) P14. Data reflect mean body mass ± SD. (n = 5–6, per group). Mean values were compared between the scrambled versus miR-29a-specific antimiR-treated mouse pups by unpaired Student's t-test. All significant differences (P < 0.05) are illustrated, and the P-value is provided above the pair of data sets.