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. 2018 Apr 30;29(8):661–677. doi: 10.1097/WNR.0000000000001015

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Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/

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Fig. 5 — Curcumin significantly attenuated apoptosis after DAI. (a) TUNEL assay was used to detect apoptotic cells in the cortex of rats in each group. Immunohistochemistry of cleaved caspase-3 was performed to assess apoptosis in each group. Scale bar=100 μm. (b) The bar graphs show the results for the numbers of TUNEL and cleaved caspase-3-positive cells in each group. Values are presented as the mean±SD (n=4; *P<0.05, compared with the control group; ^#P<0.05, compared with the DAI+vehicle group). CUR, curcumin; DAI, diffuse axonal injury.