Table 1.

Impacts on organ transplantation

Impact on transplantation	Perfusion	High subzero	Cryobanking
Expanding the donor pool	x
Ex-vivo functional assessment	x
Ex-vivo immunomodulation	x
Ex-vivo functional enhancement	x
Increasing organ utilization	x	x	x
Improving transplant outcomes	x	x	x
Immune tolerance induction	x	x	x
Disease screening	x	x	x
Reduced procurement costs	x	x	x
Reduced postoperative complications	x	x	x
Increased use of marginal organs	x	x	x
Improved matching for disadvantaged patients	x	x	x
Geographic constraints	x	x	x
Increased hand, limb transplant	x	x	x
Donor–recipient matching	x	x	x
Increased organ quality	x	x	x
Reduced postoperative costs	x	x	x
Elective scheduling of surgery		x	x
On-demand for acute conditions			x
Backup transplant organs			x
Fertility protection for recipients with cancer			x
Off-the-shelf research organs and tissues			x
Future transplant of today's marginal organs			x
Global organ matching			x
Xenotransplantation supply chain			x

Some impact, including indirect, exists for almost all relationships between the aspects of transplantation shown and each preservation modality; however, the most direct and dramatic impacts are indicated with an ‘x.’