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IL-35-producing B cells were associated IL-10-producing B cells. (A) Gating criteria from the peripheral blood for the live CD19+B cells and IL-10-producing B cells of GC patients are shown. (B) The frequency of IL-35-producing B cells was positively correlated with the frequency of IL-10-producing B cells (r = 0.6315, P = .0007, n = 25). A correlation analysis was performed using Spearman rank correlation. GC = gastric cancer, IL-35 = Interleukin 35.
