Figure 5.

IL-35-producing B cells were associated with other immune cell subsets and CD14⁺ monocytes. (A, B, C) The frequency of IL-35-producing B cells was not correlated with the frequency of CD3⁺, CD4⁺, or CD8⁺ T cells (D, E, F) and was also not correlated with the frequency of activated CD4⁺ T cells and memory CD4⁺ T cells, and (G, H) with the frequency of activated CD8⁺ T cells. (I) The frequency of IL-35-producing B cells was positively correlated with the frequency CD14⁺ monocytes (r = 0.4353, P = .03, n = 25). A correlation analysis was performed using Spearman rank correlation. IL-35 = Interleukin 35.