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. Author manuscript; available in PMC: 2018 Aug 21.
Published in final edited form as: Pediatr Res. 2018 Feb 21;83(5):1057–1066. doi: 10.1038/pr.2018.13

Figure 4. Viral loads in reovirus-infected WT, IFNAR−/−, and RAG2−/− mice.

Figure 4

WT, IFNAR−/−, and RAG2−/− mice were inoculated intracranially with reovirus T3D at 100 PFU/g at either 4 or 15 d of age. At 4, 7, and 10 d p.i., mice were euthanized, organs resected, and viral loads were determined. Viral loads in brains of mice inoculated at (a) 4 or (b) 15 d of age, in hearts of mice inoculated at (c) 4 or (d) 15 d of age, in spleens of mice inoculated at (e) 4 or (f) 15 d of age, in livers of mice inoculated at (g) 4 or (h) 15 d of age, and in intestines of mice inoculated at (i) 4 or (j) 15 d of age. N = 2–10 except IFNAR−/− 10 d p.i., for which n = 1 due to low survival rate at that time point. Dotted lines represent limit of detection. *, P < 0.05; **, P < 0.01 as determined by Mann-Whitney U test.