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. Author manuscript; available in PMC: 2018 Aug 21.
Published in final edited form as: Pediatr Res. 2018 Feb 21;83(5):1049–1056. doi: 10.1038/pr.2018.6

Figure 3. HMGB1 expression in rat lungs.

Figure 3

(A) qPCR and (B) ELISA analysis were performed to determine respectively mRNA and protein expression of HMGB1 in lung tissues of rat pups infected with rrRSV at 10 d of life and killed 5 d later. Both HMGB1 mRNA and protein increased significantly in the lungs of rrRSV-infected rats compared to pathogen-free controls. (C) Increased HMGB1 protein expression in rrRSV-infected rat lungs was confirmed by Western blot. (D) Densitometry analysis. Data are expressed as mean ± SEM. **P<0.01, ***P<0.001 compared to non-infected cells. All experiments were repeated at least three times.