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. Author manuscript; available in PMC: 2019 May 17.
Published in final edited form as: Cell Chem Biol. 2018 Mar 15;25(5):540–549.e4. doi: 10.1016/j.chembiol.2018.02.008

Figure 5. Phylogenomic Analysis of PumJ Sequences.

Figure 5

(A) Enlargement of the phylogenetic tree (panel B) with PumJ-related sequences from families 1 and 2 and the corresponding gene clusters, each centered on the PumJ homolog. The predicted enzymatic functions are color-coded as indicated in the side panel. The pum cluster is indicated as “PumJ.” Clusters from families 1 and 2 are shown in greater detail as Figures S6 and S7. Selected BGCs from family 3 are reported in Figure 6.

(B) A phylogenetic tree of ~7,000 TruD sequences. The tree was rooted with a set of TruB enzymes. The branches representing families 1, 2, and 3 are shown in red, blue, and green, respectively.

See also Figures 6, S6, and S7.

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