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. Author manuscript; available in PMC: 2019 May 17.
Published in final edited form as: Cell Chem Biol. 2018 Mar 22;25(5):585–594.e7. doi: 10.1016/j.chembiol.2018.02.010

Figure 5. NSC319726 induces reactive oxygen species generation.

Figure 5

(A) ROS measurement using CM-H2DCFDA upon NSC319726 and/or Cu(II) treatment. (B) The effect of N-acetylcysteine (NAC) supplementation on the lethality of NSC319726. (C) Abundance of 2′-deoxyguanosine upon NSC319726 and/or Co(II) supplementation. (D) Cell cycle analysis using Nuclear ID Red staining upon treatment of NSC319726/7Br8HQ/MB. Error bars in (B) indicate SEM of technical triplicates. See also Figures S5–8.