Table 2.
Multivoxel Pattern Analysis (MVPA) Classification Results in High Risk (HR), Healthy Volunteer (HV) and Depressed Not-Recently Medicated (NRM) Major Depressive Disorder (MDD) Subjects (AUC = area under the receiver operating characteristic curve)
Classification | mean AUC | mean AUC p-value | peak AUC | sensitivity | specificity | p-value |
---|---|---|---|---|---|---|
Depressed NRM MDD (N=29) vs. HV (N=51) | 0.58 | 0.17 | 0.62 | 0.5 | 0.74 | 0.08 |
HR (N=9) vs. HV (N=51) | 0.80 | < 0.005 | 0.87 | 0.78 | 0.96 | 0.00025* |
HR (N=9) vs. Depressed NRM MDD (N=29) | 0.49 | 0.43 | 0.61 | 0.56 | 0.67 | 0.098 |
denotes p < 0.05 after Bonferroni Correction.