Table 5.

Association between SNPs and endpoints with a significant correlation in the exploration cohort

Endpoint	Factor	Genotype	Univariable
			OR (95% CI)	p-value
Elevated transaminases (any grade)	PTPN11 333–223A>G	GG + AG vs. AA	1.509 (0.690–3.300)	0.301a
Treatment-related adverse events (any grade)	PDCD1 804C>T	TT vs. CC + CT	0.923 (0.449–1.899)	0.828a
Rheumatological toxicity (any grade)	IFNG -1616T>C	CC vs. TT + TC	0.477 (0.059–3.857)	0.695b

OR odds ratio, CI confidence interval.

^aχ² test was used.

^bFisher’s Exact test was used