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. 2018 May 18;8:7868. doi: 10.1038/s41598-018-26277-9

Table 2.

Univariate analysis of microbiological parameters associated with treatment failure and 30-day mortality in 147 episodes of bacteremia due to MRSA with vancomycin MIC = 2 mg/L in a teaching hospital in Taiwan, 2009–2011.

Factor Total (n = 147) Treatment response 30-day outcome
Failure
(n = 79)
Success
(n = 68)
P value Died Survived P value
Resistance to
 Daptomycin (%) 11 (7.48) 8 (10.1) 3 (4.41) 0.1892 4 (8.51) 7 (7.00) 0.7448
  Fusidic acid (%) 11 (7.48) 6 (7.59) 5 (7.35) 0.9577 3 (6.38) 8 (8.00) 1.000*
 Linezolid (%) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
 TMP-SXT (%) 108 (73.5) 62 (78.5) 46 (67.7) 0.1380 37 (78.7) 71 (71.0) 0.3226
 Teicoplanin (%) 2 (1.36) 0 (0) 2 (2.94) 0.2123 0 (0) 2 (2.00) 1.000*
 Tigecycline (%) 5 (3.40) 4 (5.06) 1 (1.47) 0.3735 3 (6.38) 2 (2.00) 0.3276
 Rifampin (%) 38 (25.9) 23 (29.1) 15 (22.1) 0.3300 16 (34.0) 22 (22.0) 0.1199
hVISA phenotype 55 (37.4) 38 (48.1) 17 (25.0) 0.0039 24 (51.1) 31 (31.0) 0.0191
Delta-hemolysis 106 (72.1) 55 (69.6) 51 (75.0) 0.4683 31 (66.0) 75 (75.0) 0.2542
Agr type 0.2533 0.6534
 Type 1 123 (83.7) 69 (87.3) 54 (79.4) 41 (87.2) 82 (82.0)
 Type 2 21 (14.3) 10 (12.7) 11 (16.2) 6 (12.8) 15 (15.0)
 Type 4 2 (1.36) 0 (0) 2 (2.94) 0 (0) 2 (2.00)
 untypable 1 (0.68) 0 (0) 1 (2.94) 0 (0) 1 (1.00)
SCCmec type 0.0072 0.2801
 II 16 (10.9) 10 (12.7) 6 (8.82) 6 (12.8) 10 (10.0)
 III 105 (71.4) 63 (79.8) 42 (61.8) 37 (78.7) 68 (68.0)
 IV 19 (12.9) 6 (7.59) 13 (19.1) 4 (8.51) 15 (15.0)
 V 4 (2.72) 0 (0) 4 (5.88) 0 (0) 4 (4.00)
 untypable 3 (2.04) 0 (0) 3 (4.41) 0 (0) 3 (3.00)
PVL genes 1 (0.68) 0 (0) 1 (1.47) 0.4626* 0 (0) 1 (1.00) 1.000*

*Fisher’s exact test.