Table 3.
Treatment rate ratios for radiotherapy alone (RT) within 6 months of diagnosis of lung, oesophageal, pancreatic and stomach cancers in 2013–2014, from a fully adjusted multivariable model with sex, age at diagnosis deprivation, ethnicity and Charlson comorbidity index, stratified by cancer site
| NSCLC | SCLC | Oesophagus | Stomach | Pancreas | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| %a | TRR (95% CI) | %a | TRR (95% CI) | %a | TRR (95% CI) | %a | TRR (95% CI) | %a | TRR (95% CI) | |
| Sex | ||||||||||
| Male | 19 | Ref | 6 | Ref | 9 | Ref | 5 | Ref | 1 | Ref |
| Female | 16 | 0.82 (0.77, 0.86) | 5 | 0.85 (0.67, 1.09) | 14 | 1.41 (1.15, 1.74) | 5 | 0.87 (0.63, 1.19) | 1 | 1.03 (0.69, 1.52) |
| p for heterogeneityb | <0.0001 | 0.19 | 0.001 | 0.39 | 0.89 | |||||
| Age at cancer diagnosis | ||||||||||
| <50 | 15 | 0.69 (0.57, 0.83) | 1 | 0.35 (0.09, 1.43) | 7 | 0.63 (0.34, 1.18) | 1 | 0.31 (0.09, 1.03) | 1 | 0.65 (0.23, 1.86) |
| 50–59 | 19 | 0.93 (0.84, 1.03) | 4 | 1.14 (0.73, 1.77) | 6 | 0.64 (0.43, 0.94) | 4 | 0.99 (0.51, 1.92) | 1 | 0.76 (0.38, 1.51) |
| 60–69 | 19 | Ref | 4 | Ref | 9 | Ref | 4 | Ref | 2 | Ref |
| 70–79 | 19 | 1.13 (1.06, 1.21) | 6 | 1.76 (1.28, 2.40) | 12 | 1.34 (1.04, 1.72) | 6 | 1.80 (1.15, 2.80) | 2 | 1.03 (0.63, 1.66) |
| 80+ | 15 | 0.96 (0.89, 1.04) | 10 | 3.58 (2.54, 5.05) | 14 | 1.86 (1.42, 2.44) | 7 | 2.56 (1.64, 4.00) | 1 | 0.82 (0.46, 1.45) |
| p for heterogeneityb | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.78 | |||||
| Charlson comorbidity index | ||||||||||
| 0 | 18 | Ref | 5 | Ref | 10 | Ref | 5 | Ref | 1 | Ref |
| 1 | 16 | 0.93 (0.85, 1.01) | 5 | 0.95 (0.64, 1.42) | 9 | 0.89 (0.63, 1.26) | 7 | 1.48 (0.99, 2.22) | 2 | 1.64 (0.97, 2.76) |
| 2 | 16 | 0.94 (0.84, 1.05) | 7 | 1.43 (0.93, 2.19) | 13 | 1.14 (0.74, 1.74) | 7 | 1.32 (0.77, 2.26) | 1 | 0.79 (0.29, 2.16) |
| 3+ | 15 | 0.92 (0.82, 1.04) | 10 | 1.80 (1.17, 2.77) | 10 | 0.97 (0.60, 1.56) | 7 | 1.27 (0.66, 2.42) | 2 | 1.55 (0.67, 3.59) |
| p for heterogeneityb | 0.19 | 0.02 | 0.83 | 0.23 | 0.20 | |||||
| Deprivation quintile | ||||||||||
| 1: least deprived | 18 | Ref | 5 | Ref | 11 | Ref | 5 | Ref | 2 | Ref |
| 2 | 18 | 1.01 (0.92, 1.11) | 7 | 1.30 (0.85, 1.99) | 11 | 1.07 (0.79, 1.45) | 6 | 1.11 (0.71, 1.74) | 1 | 0.72 (0.40, 1.28) |
| 3 | 18 | 1.10 (1.01, 1.21) | 5 | 1.02 (0.66, 1.57) | 11 | 1.03 (0.76, 1.39) | 6 | 1.01 (0.63, 1.60) | 2 | 0.87 (0.51, 1.51) |
| 4 | 17 | 1.05 (0.96, 1.15) | 5 | 1.15 (0.75, 1.74) | 10 | 0.96 (0.71, 1.32) | 5 | 0.92 (0.58, 1.48) | 1 | 0.65 (0.34, 1.22) |
| 5: most deprived | 18 | 1.11 (1.02, 1.21) | 4 | 0.97 (0.63, 1.47) | 9 | 0.87 (0.63, 1.21) | 4 | 0.66 (0.39, 1.11) | 1 | 0.67 (0.35, 1.29) |
| p for heterogeneityb | 0.05 | 0.49 | 0.77 | 0.31 | 0.58 | |||||
| Ethnicity | ||||||||||
| White | 18 | Ref | 5 | Ref | 10 | Ref | 5 | Ref | 1 | Ref |
| Non-white | 18 | 0.86 (0.75, 1.00) | 8 | 1.32 (0.68, 2.59) | 12 | 1.24 (0.68, 2.28) | 6 | 1.68 (0.99, 2.86) | 2 | 1.19 (0.51, 2.78) |
| Unknown | 15 | 0.89 (0.76, 1.04) | 8 | 1.82 (0.99, 3.35) | 5 | 0.52 (0.26, 1.05) | 5 | 1.22 (0.54, 2.77) | 2 | 1.66 (0.72, 3.82) |
| p for heterogeneityb | 0.05 | 0.12 | 0.14 | 0.15 | 0.46 | |||||
CI confidence interval, NSCLC non-small cell lung cancer, SCLC small cell lung cancer, TRR treatment rate ratio.
a Proportion of patients recorded to receive treatment in each category.
b Performed jointly across all categories of each variable, using a post-estimation Wald test