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. 2018 Apr 26;118(10):1322–1328. doi: 10.1038/s41416-018-0085-y

Table 2.

Treatment-induced changes in circulating Flt3L levels and correlations with cytotoxic effects – Oslo study

Measure of cytotoxicity Post NACT Post CRT
N r P N r P
Haemoglobin 56 –0.38 <0.01 49 0.02 0.87
Thrombocytes 56 –0.07 0.62 49 –0.34 0.02
Neutrophils 56 –0.36 0.01 49 –0.19 0.19
Lymphocytes 54 0.27 0.05 47 0.11 0.46
Monocytes 53 0.07 0.60 40 0.47 0.01
Tumour ΔVa 49 –0.32 0.03 43 0.07 0.67

CRT chemoradiotherapy, Flt3L fms-like tyrosine kinase 3 ligand, NACT neoadjuvant chemotherapy

aΔV denotes ∆VNACT post NACT and ∆VCRT post CRT