Table 2.
Treatment-induced changes in circulating Flt3L levels and correlations with cytotoxic effects – Oslo study
| Measure of cytotoxicity | Post NACT | Post CRT | ||||
|---|---|---|---|---|---|---|
| N | r | P | N | r | P | |
| Haemoglobin | 56 | –0.38 | <0.01 | 49 | 0.02 | 0.87 |
| Thrombocytes | 56 | –0.07 | 0.62 | 49 | –0.34 | 0.02 |
| Neutrophils | 56 | –0.36 | 0.01 | 49 | –0.19 | 0.19 |
| Lymphocytes | 54 | 0.27 | 0.05 | 47 | 0.11 | 0.46 |
| Monocytes | 53 | 0.07 | 0.60 | 40 | 0.47 | 0.01 |
| Tumour ΔVa | 49 | –0.32 | 0.03 | 43 | 0.07 | 0.67 |
CRT chemoradiotherapy, Flt3L fms-like tyrosine kinase 3 ligand, NACT neoadjuvant chemotherapy
aΔV denotes ∆VNACT post NACT and ∆VCRT post CRT