Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 18;194(6):560–569. doi: 10.1007/s00066-018-1262-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 2 — Clinical validation of plan quality of the in silico SRS treatment plans with artificially contoured BM compared to clinically delivered SRS treatment plans in BM patients. A comparison of the single-fraction IDP dose level with V_12Gy = 10 cm³ for coplanar beam arrangement and GTV-PTV margin of 2 mm between perfectly spherical GTVs (filled dots) and non-spherical GTVs of clinical plans (open dots). Legend: Gy Gray, GTV gross tumor volume, PTV planning target volume, SRS stereotactic radiosurgery, BM brain metastases, IDP isotoxic dose prescription, V₁₂_G_y volume of healthy brain tissue which is irradiated to 12 Gray or more. The solid lines represent single-fraction PTV size-based dose prescription protocols. The dashed line represents a logistic regression model fitted to data of perfectly spherical GTVs