Table 2.

Tissue contents of endogenous Cbl in normal and Cbl-deficient rats

	Deficient n = 6		Normal n = 6
	pmol Cbl/g	Whole-organ Cbl (pmol)	pmol Cbl/g	Whole-organ (pmol)
Liver	20 (18–27)	270 (210–330)	29 (28–30)	370 (325–400)
Kidneys	85 (73–97)	190 (165–225)	1160 (1000–1270)	2400 (2110–2900)
Spleen	10 (9–12)	8 (6–10)	25 (24–29)	20 (15–25)
Heart	28 (27–28)	29 (24–40)	49 (47–51)	51 (47–54)
Brain	13 (12–15)	24 (21–28)	23 (23–24)	45 (43–47)
Muscle	6 (5–8)	635 (465–775)	10 (8–11)	1010 (885–1140)

Rats were kept for 2 weeks on a Cbl-deficient diet or control diet prior to sacrifice. Results are expressed as mean and (range)